Upcoming Match-ups

NFL Divisional Round Odds – Opening Lines and Spreads for All 4 Playoff Games

John Perrotto

by John Perrotto in NFL Football

Updated Jan 17, 2022 · 8:58 PM PST

Patrick Mahomes passing
Kansas City Chiefs quarterback Patrick Mahomes (15) throws a 4-yard touchdown pass to running back Jerick McKinnon, right, during the first half of an NFL wild-card playoff football game, Sunday, Jan. 16, 2022, in Kansas City, Mo. (AP Photo/Colin E. Braley)
  • The field is set for the divisional round of the NFL Playoffs
  • The Chiefs opened as 2.5-point home favorites over the Bills in a rematch of last year’s AFC Championship Game
  • A look at the matchups and opening odds can be found below

The matchups are set for the four divisional round games in the NFL Playoffs.

In the AFC, the Tennessee Titans (12-5) will host the Cincinnati Bengals (11-7) at 4:30pm ET Saturday and the Buffalo Bills (12-6) will visit the Kansas City Chiefs (13-5) at 6:30pm ET Sunday.

In the NFC, the San Francisco 49ers (11-7) play at the Green Bay Packers (13-4) at 8:15pm ET Saturday and the Tampa Bay Buccaneers (14-4) are home against the Los Angeles Rams (13-5) at 3pm ET Sunday.

Let’s run down NFL Division Playoff Opening odds.

NFL Divisional Playoff Opening Odds

Team Moneyline Spread Over/Under
Cincinnati Bengals +140 +3 (-105) Over 47.5 (-110)
Tennessee Titans -166 -3 (-115) Under 47.5 (-110)
Team Moneyline Spread Over/Under
San Francisco 49ers +180 +5 (-110) Over 47 (-110)
Green Bay Packers -215 -5 (-110) Under 47 (-110)
Team Moneyline Spread Over/Under
Los Angeles Rams +126 +3 (118) Over 48 (-110)
Tampa Bay Buccaneers -148 -3 (-104) Under 48 (-110)
Team Moneyline Spread Over/Under
Buffalo Bills +114 +2.5 (-110) Over 53 (-106)
Kansas City Chiefs -134 -2.5 (-110) Under 53 (-106)

Odds as of January 17th at FanDuel.

Bengals vs Titans

The top-seeded Titans had the AFC’s lone bye after finishing the regular season on a three-game winning streak. The Bengals have won four of their last five after beating the Las Vegas Raiders 26-19 on Saturday at home in a wild card playoff.

Joe Burrow led the Bengals to their first playoff victory since 1991 by throwing two touchdown passes and rookie Even McPherson kicked four goals. Burrow completed 24-of-34 passes for 244 yards.

The Bengals survived a scare in the final minute. The Raiders drove to the Cincinnati 9-yard line but Germaine Pratt intercepted Derek Carr’s fourth-down pass with 17 seconds left.

The Titans opened as a three-point favorite and that spreads figures to hold steady.

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49ers vs Packers

While the #1-seed Packers had the NFC’s top seed and resultant bye, the 49ers beat the Dallas Cowboys 23-17 on Sunday on the road. San Francisco won its third straight and for the fifth time in their last six games.

Wide receiver Deebo Samuel had a 26-yard touchdown run one play after a Dak Prescott interception to put the 49ers ahead 23-7 with 5:50 remaining in the third quarter. Samuel rushed for 72 yards on 10 carries and caught three passes for 38 yards.

The Cowboys had a last chance with the ball at the San Francisco 41 with 14 seconds to go. Prescott took off up the middle for a 17-yard gain, but Dallas was unable to get off another play before time expired.

The Packers opened as a five-point favorite and the number immediately dipped to four before going back up to 4.5 points. It would be surprising if the line went above five.

Rams vs Buccaneers

The Rams rolled to a 34-11 victory over the Arizona Cardinals on Monday night at home for their sixth win in the last seven games.

Matthew Stafford led the way for the Rams as he passed for 202 yards and two touchdowns and ran for another score. It was the first playoff victory of the 13-year veteran’s career.

Odell Beckham Jr. and Cooper Kupp caught Stafford’s scoring throws. David Long’s 3-yard interception return for a touchdown in the second quarter gave the Rams a commanding 21-0 lead.

The Buccaneers disposed of the visiting Philadelphia Eagles 31-15 on Sunday to run their winning streak to four games and notch their eighth victory in the last nine games.

Tom Brady threw for 271 yards and two touchdowns to the lead the Buccaneers, who had a pair of long TD drives in the first quarter and led 17-0 at halftime. Brady’s scoring passes went to Rob Gronkowski and Mike Evans as he improved his career playoff record to 35-11.

The Buccaneers intercepted Jalen Hurts twice in his first postseason start.

Despite being the defending Super Bowl champions and playing at home, the Buccaneers have opened as just three-point chances. That line figures to rise because Brady is always a favorite of the betting public.

Bills vs Chiefs

In a rematch of last season’s AFC Championship Game won by the Chiefs, the Bills will come in on a five-game winning streak while Kansas City has won 10 of its last 11.

Josh Allen set a Bills’ playoff record with five touchdown passes, including two to Dawson Knox, as Buffalo rolled over the New England Patriots 47-17 on Saturday night in Orchard Park. Devin Singletary ran for two scores.

Allen finished 21-of-25 for 308 yards in a game Buffalo scored on each of its seven possessions that didn’t end with a kneeldown. The Bills had 300 yards of total offense and 19 first downs in building a 27-3 halftime lead.

Patrick Mahomes threw for 404 yards and five touchdowns to lead the Chiefs over the visiting Pittsburgh Steelers 42-21 on Sunday night. Tight end Travis Kelce caught a TD pass and threw another one.

Byron Pringle scoring passes from both Mahomes and Kelce. Jerick McKinnon and Tyreek Hill also had TD catches – and so did offensive tackle Nick Allegretti.

The line opened with the Chiefs as 2.5-point favorites. However, with the Bills playing so well, it would not be surprising to see some sharp money go Buffalo’s way.

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