Rams vs 49ers Props – Best Player Prop Bets for Monday Night Football Week 4

By Chris Amberley in NFL Football
Updated: March 16, 2023 at 1:38 pm EDTPublished:

- See the latest player props for the Rams vs 49ers NFC West tilt on Monday (Oct. 3, 8:15 pm ET) in Week 4
- Get the odds for Cooper Kupp, Matthew Stafford, Deebo Samuel and more in tonight’s Rams vs 49ers Monday Night Football prop bets
- Rams vs 49ers props can be found below for MNF, along with analysis and best bets
NFC West rivals clash on Monday Night Football as the reigning Super Bowl champion Los Angeles Rams (2-1, 1-0 away) visit the San Francisco 49ers (1-2, 1-1 home) and we’re breaking down the best player props for MNF here.
This is a rematch of last season’s NFC Championship Game, one of three contests between the two teams in 2021. Each of those outings went under the total, and this game has a strong chance to underwhelm in the box score as well. As such, expectations should be kept in check for some of the matchup’s biggest stars including Cooper Kupp, Matthew Stafford and Deebo Samuel when you’re making your Rams vs 49ers player props,
Speaking of Stafford, he’s the first target in our Rams vs 49ers props card. Check out the odds below plus an analysis on which MNF prop bets to target.
Rams vs 49ers Player Props
Quarterbacks | Completions | Passing Yards | Passing TD |
---|---|---|---|
Matthew Stafford (LAR) | 23.5 (Ov -105 | Un -125) | 250.5 (Ov -115 | Un -115) | 1.5 (Ov -130 | Un -105) |
Jimmy Garoppolo (SF) | 19.5 (Ov -120 | Un -110) | 224.5 (Ov -105 | Un -130) | 1.5 (Ov +125 | Un -170) |
Running Backs | Attempts | Rush Yards | Rush + Rec Yards |
Darrell Henderson (LAR) | N/A | 22.5 (Ov -115 | Un -115) | N/A |
Cam Akers (LAR) | 12.5 (Ov -125 | Un -105) | 43.5 (Ov -110 | Un -120) | 54.5 (Ov -115 | Un -115) |
Jeff Wilson Jr. (SF) | 15.5 (Ov +100 | Un -130) | 54.5 (Ov -115 | Un -115) | 68.5 (Ov -115 | Un -115) |
Wide Receivers + Tight Ends | Receptions | Receiving Yards | Longest Reception |
Cooper Kupp (LAR) | 8.5 (Ov +115 | Un -155) | 94.5 (Ov -115 | Un -115) | 26.5 (Ov -115 | Un -115) |
Allen Robinson (LAR) | 3.5 (Ov +100 | Un -135) | 38.5 (Ov -115 | Un -115) | 17.5 (Ov -115 | Un -115) |
Ben Skowronek (LAR) | N/A | 32.5 (Ov -125 | Un -115) | 16.5 (Ov -115 | Un -115) |
Tyler Higbee (LAR) | 4.5 (Ov +100 | Un -135) | 42.5 (Ov -115 | Un -115) | 17.5 (Ov -115 | Un -115) |
Deebo Samuel (SF) | 4.5 (Ov -150 | Un +115) | 56.5 (Ov -115 | Un -115) | 22.5 (Ov -115 | Un -115) |
Brandon Aiyuk (SF) | 4.5 (Ov +115 | Un -155) | 52.5 (Ov -115 | Un -115) | 21.5 (Ov -115 | Un -115) |
Jauan Jennings (SF) | 1.5 (Ov -120 | Un -110) | 16.5 (Ov -115 | Un -115) | 12.5 (Ov -115 | Un -115) |
George Kittle (SF) | 4.5 (Ov +115 | Un -155) | 43.5 (Ov -115 | Un -115) | 18.5 (Ov -115 | Un -115) |
Odds as of October 2nd at DraftKings Sportsbook. Get the DraftKings promo code to bet on your Rams vs 49ers props on MNF
Stafford’s passing yards over/under is 26 yards higher than Garoppolo’s, while his completions prop is four completions higher.
The Rams are currently 1.5-point underdogs in San Francisco, a place that didn’t treat LA very kindly the last time they visited.
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MNF Prop: Matthew Stafford Over 0.5 Interceptions
San Fran blew out the Rams at home last season, running all over them in a 31-10 victory. Stafford was picked off twice that night, and six times in three meetings with the 49ers last season.
He’s started the season with five interceptions through three weeks, and we’re getting a nice price in MNF props that he’ll throw at least one to the wrong team on Monday.
https://twitter.com/JackHammer_NFL/status/1575889583698345991
The 49ers enter Week 4 as the top graded coverage unit per Pro Football Focus, while no team has generated more pressure on the opposing quarterback.
Pick: Matthew Stafford Over 0.5 Interceptions (-115), 1 unit
MNF Prop: Cooper Kupp Under 8.5 Receptions
Is there a more reliable wide receiver in football than Cooper Kupp? Probably not. However, asking him to catch nine balls in his MNF player props versus this defense is a lot.
Curtis Samuel is averaging more opportunities per game (12.7) than Cooper Kupp (12)
— Adam Koffler (@AdamKoffler) October 1, 2022
Kupp is fresh off his worst game since teaming up with Stafford, and while we shouldn’t expect a repeat performance, we should expect the majority of the defensive game plan to be centered around neutralizing him.
The Niners grade out as the third-best defense per DVOA and have surrendered more than four receptions to only two enemy wideouts so far.
Pick: Cooper Kupp Under 8.5 receptions (-155), 1 unit
Rams vs 49ers Touchdown Scorer Props
Player | Odds to Score 1st TD | Odds to Score Anytime TD |
---|---|---|
Cooper Kupp (LAR) | +550 | -110 |
Jeff Wilson Jr. (SF) | +700 | +120 |
Deebo Samuel (SF) | +750 | +130 |
Cam Akers (LAR) | +850 | +150 |
George Kittle (SF) | +950 | +175 |
Brandon Aiyuk (SF) | +1000 | +190 |
Allen Robinson (LAR) | +1300 | +235 |
Darrell Henderson Jr. (LAR) | +1400 | +235 |
Tyler Higbee (LAR) | +1400 | +250 |
Ben Skowronek (LAR) | +1900 | +380 |
Jauan Jennings (SF) | +2200 | +450 |
Jordan Mason (SF) | +2500 | +550 |
Jimmy Garoppolo (SF) | +3000 | +650 |
49ers Defense | +3000 | +650 |
Rams Defense | +3500 | +700 |
Kyle Juszczyk (SF) | +4000 | +800 |
MNF Prop: George Kittle Anytime TD
Monday would be an excellent time for George Kittle to finally get on the board in Rams vs 49ers picks. The 49ers’ tight end is arguably one of the most talented pass catchers at that position, but San Fran doesn’t choose to deploy him in that role nearly as often as they should.
JIMMY G🎯GEORGE KITTLE = ¡¡ENORME TOUCHDOWN!!🔥😎#FTTB | #NFL
pic.twitter.com/gm7xdkyU9r— Holy Roller NFL (@HolyRollerNFL) January 31, 2022
Kittle has scored five career touchdowns against the Rams, three more than versus any other team. The Rams grade out as just a league-average unit against the pass this season and have allowed opponents to convert 50% of their red zone opportunities into touchdowns. Kittle looks like great value to get his first TD in Monday’s Rams vs 49ers props.
Pick: George Kittle Anytime TD (+175), 1 unit

Sports Writer
As SBD's resident Swiss Army Knife, Chris covers virtually every sport including NFL, PGA, NBA, MLB, NCAAB, NCAAF and the Olympics. A true grinder, he'd rather pick off small edges in the player props market than swing for the fences with a 5-leg parlay.