Upcoming Match-ups
Today
24
Apr
7:00 PM
MIA
BOS
+15
-15
203
9:30 PM
NO
OKC
+7.5
-7.5
211
Tmrw
25
Apr
7:00 PM
CLE
ORL
+1
-1
199
7:30 PM
NY
PHI
+4.5
-4.5
204
10:00 PM
DEN
LAL
-1
+1
216.5
Friday
26
Apr
5:30 PM
MIL
IND
+4.5
-4.5
224.5
8:00 PM
LAC
DAL
+4
-4
209
10:30 PM
MIN
PHO
+3.5
-3.5
208.5
  1. Home
  3. NFL Football
  5. NFL Odds
  7. Buffalo Bills VS New Orleans Saints

Buffalo Bills VS New Orleans Saints

Football Icon
Odds & Matchup Stats
Buffalo Logo

Buffalo

6-4

vs
New Orleans Logo

New Orleans

5-5

November 25, 2021

8:20 PM EST

Caesars Superdome

Closing Odds

Matchupfanduel Logodraftkings Logobetmgm LogoBet %Money %Consensus
Buffalo Team LogoBuffalo
-6.5 -114
-7 -110
-7 -110
88%
New Orleans Team LogoNew Orleans
+6.5 -106
+7 -110
+7 -110
12%

This game was played on November 25, 2021. Closing Odds were accurate as of 8:20 pm. Check out upcoming NFL Odds.

SHARE A LINK

SHARE THIS PAGE

Predicted Score

Buffalo Logo

24.4 - 26.8

New Orleans Logo

Our formula predicts the New Orleans Saints will beat the Buffalo Bills by a score of 26.8–24.4.

Win Probability

Buffalo Logo

70.2% - 29.8%

New Orleans Logo

The Bills have a 70.2% chance of beating the Saints based off the odds.

Pick

New Orleans Logo

New Orleans To Win

Saints COVER the +6.5 spread and the total is OVER 45

SportsBettingDime’s formula is picking the Saints (+6.5) to cover the spread, and has the total going Over 45.

Consensus
Picks

Buffalo Team Logo
New Orleans Team Logo
50%
50%
50%
50%
50%
50%
MLATSO/U

Trends

Buffalo Team Logo

Buffalo

New Orleans Team Logo

New Orleans

The Bills lost their last game.

RETURN ON INVESTMENT: LAST 10 GAMES

Date
ML
ATS
OVER
UNDER

KEY INSIGHT: Available exclusively for SBD Plus users. Login or Register for FREE.

Buffalo Team Logo

Buffalo

The Bills lost their last game.

RETURN ON INVESTMENT: LAST 10 GAMES

Date
ML
ATS
OVER
UNDER

KEY INSIGHT: Available exclusively for SBD Plus users. Login or Register for FREE.

New Orleans Team Logo

New Orleans

The Saints lost their last 3 games.

RETURN ON INVESTMENT: LAST 10 GAMES

Date
ML
ATS
OVER
UNDER

KEY INSIGHT: Available exclusively for SBD Plus users. Login or Register for FREE.

Understanding Return on Investment Trends

SBD Sharp measures the profitability of teams over time. A positive percentage indicates that betting the team has been profitable in recent games. Visit SBD Sharp for a detailed explanation of ROI trends or register for your free SBD Plus account account today.

Futures Trackers

Track the Super Bowl odds all season and see how Buffalo and New Orleans compare to the top contenders.

Learn More

Stats

Records

Buffalo Logo

Buffalo

New Orleans

New Orleans Logo
6-4

Overall

5-5
3-2

Away/Home

2-2
10-5Fav/Udog4-5

Each team's record on the moneyline, spread, and over/under, with home and road splits for each.

Team Leaders

Buffalo Logo

Josh Allen

Trevor Siemian

New Orleans Logo
281.1

Passing YPG

230
21

Passing TDs

8
8

INTs

2

Compare key stats for each team's most impactful players.

Head to Head

Buffalo Logo

Buffalo

New Orleans

New Orleans Logo
Points Per Game (PPG)
29.5
25.1
Yards Per Game (YPG)
392.1
321.3
Passing Yards Per Game
273.3
203.4
Rushing Yards Per Game
118.8
117.9
Turnovers Committed
14
11
Points Per Game Allowed
17.6
21.8
Yards Per Game Allowed
283.7
342
Passing Yards Per Game Allowed
181.8
252.2
Rushing Yards Per Game Allowed
101.9
89.8
Turnovers Forced
22
14

Directly compare team stats for the most important metrics.

Injuries

Buffalo Team Logo

Buffalo

New Orleans Team Logo

New Orleans

PlayerStatus

Cam Lewis

out

Illness

11/25/2021 @ 7:30PM EST

Marquez Stevenson

probable

Head

11/25/2021 @ 5:12PM EST

Cole Beasley

probable

Ribs

11/24/2021 @ 11:31AM EST

Tremaine Edmunds

probable

Hamstring

11/22/2021 @ 10:58PM EST

Spencer Brown

I-R

Illness

11/18/2021 @ 11:17AM EST

Star Lotulelei

I-R

Illness

11/15/2021 @ 7:36PM EST

Justin Zimmer

I-R

Foot

11/11/2021 @ 5:48PM EST

Jon Feliciano

I-R

Calf

11/06/2021 @ 7:51PM EDT

Bryan Cox Jr.

out

Achilles

06/22/2021 @ 8:59PM EDT

-

-

Buffalo Team Logo

Buffalo

PlayerStatus

Cam Lewis

out

Illness

11/25/2021 @ 7:30PM EST

Marquez Stevenson

probable

Head

11/25/2021 @ 5:12PM EST

Cole Beasley

probable

Ribs

11/24/2021 @ 11:31AM EST

Tremaine Edmunds

probable

Hamstring

11/22/2021 @ 10:58PM EST

Spencer Brown

I-R

Illness

11/18/2021 @ 11:17AM EST

Star Lotulelei

I-R

Illness

11/15/2021 @ 7:36PM EST

Justin Zimmer

I-R

Foot

11/11/2021 @ 5:48PM EST

Jon Feliciano

I-R

Calf

11/06/2021 @ 7:51PM EDT

Bryan Cox Jr.

out

Achilles

06/22/2021 @ 8:59PM EDT

-

-

New Orleans Team Logo

New Orleans

PlayerStatus

Mark Ingram II

out

Knee

11/25/2021 @ 1:49PM EST

Trevor Siemian

probable

Hand

11/24/2021 @ 6:40PM EST

Taysom Hill

probable

Foot

11/24/2021 @ 6:39PM EST

Ryan Ramczyk

out

Knee

11/24/2021 @ 6:38PM EST

Tanoh Kpassagnon

out

Ankle

11/24/2021 @ 6:38PM EST

Alvin Kamara

out

Knee

11/24/2021 @ 6:37PM EST

Marcus Davenport

out

Shoulder

11/24/2021 @ 6:37PM EST

Ty Montgomery

probable

Hand

11/23/2021 @ 10:5PM EST

Landon Young

I-R

Foot

11/23/2021 @ 6:46PM EST

Adam Trautman

I-R

Knee

11/23/2021 @ 6:46PM EST

All NFL Odds