Penn State vs Purdue Odds, Spread and Predictions

By Robert Duff in College Football
Published:

- The Penn State Nittany Lions are 3.5-point road favorites over the Purdue Boilermakers in a college football game slated for Thursday, September 1
- The Nittany Lions are 9-0 straight up in the last nine meetings with the Boilermakers
- Penn State hasn’t lost at Purdue since 2003
Over the past two decades, Penn State hasn’t just beaten Purdue. The Nittany Lions have put a beating on the Boilermakers.
Penn State is 9-0 straight up in the last nine games against Purdue. In the last four games, Penn State’s average margin of victory is 28.75 points.
The Nittany Lions are 10-4-1 against the spread in the past 15 meetings with the Boilermakers. Purdue is 1-6 SU in the school’s last seven home games facing Penn State.
There’s a sense, though, that this year, the situation is about to change. And oddsmakers are also respectful of that feeling.
Penn State is set as a road favorite over Purdue, but the margin is a paltry 3.5 points. The last time these two teams kicked off against each other in 2019, the Nittany Lions were the 28.5-point chalk.
Penn State vs Purdue Odds
Team | Spread | Total | Moneyline |
---|---|---|---|
Penn State Nittany Lions | -3.5 | O 52.5 (-110) | -170 |
Purdue Boilermakers | +3.5 | U 52.5 (-110) | +143 |
Odds as of August 30 at Caesars Sportsbook. See the available Caesars Sportsbook bonus code here.

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The kickoff for this game at Ross-Ade Stadium is set for 8:00 pm ET on Thursday, September 1. The weather forecast is predicting cloudy skies, 12 mph wind and a temperature of 90 degrees. The broadcast of the game can be seen on FOX Sports.
Penn State vs Purdue Betting Trends
At moneyline odds of -170, the Nittany Lions are offering an implied probability of victory of 62.96% in the NCAA betting line. A successful $10 wager on Penn State would deliver a payout of $15.90.
In terms of NCAA public betting trends, spread wagers are showing the public backing Penn State at 80% in both the handle and in bets. The Nittany Lions are also drawing 76% of handle and 72% of bets in public moneyline wagering. There’s a split on the total. The under is garnering 72% of the handle. But the over is getting 65% of the bet action.
Week 1 college football underdogs getting the most moneyline bets at @CaesarsSports:
1. Notre Dame (at Ohio State)
2. Purdue (vs. Penn State)
3. Illinois (at Indiana)Week 1 underdogs getting most moneyline dollars:
1. Florida (vs. Utah)
2. Purdue
3. West Virginia (at Pitt)— Max Meyer (@TheMaxMeyer) August 30, 2022
In NCAA future bets, the Nittany Lions are +6000 in the National Championship odds. Purdue is at +25000. Penn State is the +1400 fourth betting choice to win the Big Ten title. Â The Boilermakers are the co-seventh pick in this betting market at +2500.
Nittany Lions Punish Purdue
All-time against Purdue, Penn State is 15-3-1 SU. Upon their last visit to Ross-Ade Stadium in 2016, the Nittany Lions topped out at 62 points. That remains the most points ever surrendered by Purdue in a home game.
People forget Penn State was #4 in the nation last year playing great football. They were up at halftime on the road at #5 Iowa and Sean Clifford gets hurt and then it goes down hill from there. Great take by Herbstreit pic.twitter.com/qNUyX9y2xa
— Adam Breneman (@AdamBreneman81) August 27, 2022
Penn State is counting on sixth-year senior quarterback Sean Clifford to lead the offense. The season went south last year after he was injured in the loss to Iowa. The Nittany Lions finished ninth in the Big Ten in scoring offense (25.0 PPG), and 13th in rushing (107.8 yards per game). Penn State averaged 3.2 yards per carry.
Defensively, Penn State was #3 in the conference and sixth in the nation, allowing 17.3 PPG.
Purdue Poised For Big Things?
There’s a buzz about the Boilermakers that hasn’t been present on campus in West Lafayette, Indiana in many years. Like Penn State, they’re rolling with a sixth-year senior QB in Aidan O’Connell. The Boilermakers were the #2 passing offense in the Big Ten last season. O’Connell passed for 3,712 yards. Purdue finished the season ranking second nationally in completion percentage (70.8) and fifth in passing offense (355.4 YPG).
"Before anything else, preparation is the key to success." pic.twitter.com/Oxj7qj0Syb
— Purdue Football (@BoilerFootball) August 30, 2022
Purdue went 9-4 last season, including a pair of wins over top-25 teams in Michigan (#3) and Iowa (#2). Purdue is suiting up 12 transfers this season. They include former Iowa receivers Charlie Jones and Tyrone Tracey, who combined to catch 87 passes for the Hawkeyes last season.
Penn State vs Purdue Prediction
Purdue closed out the 2021 campaign going 5-1 SU and ATS. They’re also 4-1 ATS in the last five against Big Ten opposition. But the Boilermakers are 3-6 ATS in their last nine home games.
You already know… pic.twitter.com/zx4fhJtJEk
— Purdue Football (@BoilerFootball) August 29, 2022
While they’ve dominated the Boilermakers, recent history isn’t looking as good for the Nittany Lions. After a 4-0 start, Penn State closed out last second on a 2-6 skid SU and 3-5 ATS. There was one win over the school’s past five road games. Penn State is 11-11 SU over the past two seasons.
Pick: Purdue +3.5 (-110)
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Sports Writer
An industry veteran, Bob literally taught the course on the history of sports at Elder College. He has worked as a Sports Columnist for Postmedia, appeared as a guest on several radio stations, was the Vice President of the Society For International Hockey Research in Ontario, and written 25 books.