Opening Cowboys vs Giants Odds for Week 1 – Who’s Favored in Harbaugh’s First Game With NYG?
By Sascha Paruk in NFL News
Published:
- The first concrete matchup of the 2026-27 NFL season is set
- John Harbaugh’s New York Giants will host the Dallas Cowboys in Week 1
- See the opening Cowboys vs Giants odds for Sep.
The New York Giants (4-13, 9-8 ATS, 11-6 O/U) will officially begin the John Harbaugh era on Sunday, September 13th, when the G-Men host the Dallas Cowboys (7-9-1, 7-10 ATS, 12-4-1 O/U) at MetLife Stadium in Week 1 of the 2026-27 NFL season.
The first regular-season game officially on the docket for next season, Week 1 lines have already been posted, and oddsmakers aren’t overly optimistic that Harbaugh’s tenure will start with a bang.
Cowboys vs Giants Odds for Week 1
Odds as of May 12 at theScore Bet. Claim theScore Bet promo code to get a bonus for NFL Week 1.
The Cowboys opened as 1.5-point chalk and the line has already been bet up to DAL -2.5 with a -115 price on the Cowboys to cover (indicating the line will get bigger before it shrinks back down).
On the moneyline, Dallas is a -135 road favorite with New York priced at +115 to win. The game total is 48.5 with -110 odds each way.
Neither team is seen as a credible threat in the Super Bowl odds; Dallas is priced at +3500 (17th in the 32-team league) with NYG considerably further back at +7500 (22nd). The 2026 NFL win totals list the Cowboys at 8.5 with extra juice on the over (-130o/+110u) and the Giants at 7.5 with extra juice on the under (+110o/-130u).
Dallas is pegged as the second-best team in the NFC East, though. At +225 in the NFL divisional odds, the Cowboys only narrowly trail the Eagles (+140). The Giants have the longest odds in the quartet at +600.
Recent H2H Results: DAL vs NYG
The Cowboys have won three of the last four against the Giants over the last two years. New York’s only win came in a mean-nothing Week 18 game at the tail-end of last season.
The Giants have won three of the last four against the spread, however, including both matchups in the 2025-26 season. The last three matchups all went over the total.
Dallas was the best over bet in the entire league last year, going 12-4-1 O/U. The Giants were tied for the second-best over record at 11-6.
Both teams lost and gained a ton of new personnel. The tables below outline each team’s offseason moves (not counting draft picks). The tables start with the team’s lost production and end with production gained via trades and signings. Each player is given a “production score”, graded on a 0–100 index. The production scores measures a player’s 2025 regular-season output relative to all NFL players at their position. A score of 100 = best at the position league-wide, 50 = average, and 0 = bottom of the league.
Stats are calculated per game to account for missed time, using position-appropriate metrics. Offensive lineman are assigned their PFF grade from 2025.
Dallas Cowboys Offseason Moves
Safety Donovan Wilson, center Brock Hoffman, and edger rusher Jadeveon Clowney are the Cowboys’ most-significant losses.
Their notable additions include safety Jalen Thompson, DT Rashan Gary, and corner Cobie Durant.
New York Giants Offseason Moves
The Giants lose defensive anchor Bobby Okereke but replace him with fifth-overall pick Arvell Reese and former Bill/Bear Tremaine Edmunds.
Bookmark SBD’s NFL odds page to see the latest lines for every 2026 regular-season game.
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Managing Editor
Sascha has been working in the sports-betting industry since 2014, and quickly paired his strong writing skills with a burgeoning knowledge of probability and statistics. He holds an undergraduate degree in linguistics and a Juris Doctor from the University of British Columbia.
