Ohio State vs Indiana Player Props: Best Bets & Anytime Touchdown Picks

• Unbeaten Indiana hosts Ohio State at Memorial Stadium in a Big Ten heavyweight clash
• Two elite defenses, each allowing fewer than 14 points per game, face offenses loaded with playmakers
• Read below for my Ohio State vs Indiana player props, best bets and anytime touchdown picks

---

Indiana (6-0) puts a 22-game winning streak on the line when Ohio State (5-1) visits Memorial Stadium in Bloomington on Saturday, October 17. Kickoff is set for noon ET in one of the biggest Big Ten games of the season.

Both defenses have been outstanding. Indiana allows 11.8 points per game and Ohio State allows 13.2, so every yard in the prop market will be earned.

I combed through the season numbers for each team’s top playmakers to find where the value sits. Here are my favorite Ohio State vs Indiana player props, plus one anytime touchdown pick.

Ohio State vs Indiana Player Props

Odds as of October 17. Claim the BetMGM promo code before placing these Ohio State vs Indiana player props.

My card leans on Ohio State’s passing game and Indiana’s ground attack. Indiana’s elite run defense should push the Buckeyes to the air, while Indiana’s backfield gives the Hoosiers their best scoring path. For more options across the slate, check out our full list of college football player props.

OSU vs Indiana Prop Bet #1: Julian Sayin Passing Yards

Julian Sayin has completed 116 of 163 passes for 1,772 yards and 17 touchdowns through six games, averaging 295.3 passing yards per game. That production sits well above this 257.5 line, and I expect Ohio State’s game plan to run through him again on Saturday.

Indiana’s defense is strong across the board, allowing 188.5 passing yards and only 75.0 rushing yards per game. That stout run defense is exactly why I like Sayin here, since the Buckeyes’ most reliable path to moving the ball is through the air.

Sayin threw for 242 yards and four touchdowns on 13 of 21 passing against Maryland last week. He also has a proven connection with his top target, having thrown 23 career touchdown passes to Jeremiah Smith.

• Pick: Julian Sayin Over 257.5 Passing Yards (-120 at BetMGM)

OSU vs Indiana Prop Bet #2: Jeremiah Smith Receiving Yards

Jeremiah Smith has 48 receptions for 916 yards and 11 touchdowns through six games, an average of 152.7 receiving yards per game. He is just 84 yards away from his third 1,000-yard season, a pace that keeps him firmly in the conversation in the Heisman Trophy odds.

Indiana’s 188.5 passing yards allowed per game make this a legitimate test. Still, the same logic behind the Sayin pick applies here. If the Hoosiers’ run defense forces Ohio State to throw, Smith is the biggest beneficiary of that volume.

Smith finished with four catches for 93 yards and two touchdowns against Maryland last week. His season average gives this 135.5 line a comfortable cushion, and I like the Over in this Ohio State vs Indiana player prop.

• Pick: Jeremiah Smith Over 135.5 Receiving Yards (-115 at BetMGM)

OSU vs Indiana Prop Bet #3: Turbo Richard Anytime Touchdown

Indiana’s backfield has been productive all season. Turbo Richard has 597 rushing yards, and he pairs with Lee Beebe Jr. (551 yards) to give the Hoosiers 1,148 rushing yards from their top two backs.

Ohio State’s run defense is a real obstacle, allowing 96.2 rushing yards per game and only three individual 100-yard rushers since 2024. An anytime touchdown does not require a big yardage day, though, and Richard’s role in Indiana’s ground game gives him multiple chances to find the end zone.

At -111, Richard is my top Ohio State vs Indiana anytime touchdown pick. It is a near-even price for a back central to how Indiana moves the ball, and I expect the Hoosiers to lean on him in scoring position.

• Pick: Turbo Richard Anytime Touchdown (-111 at BetMGM)

Ohio State vs Indiana Weather Forecast

The National Weather Service forecast for Bloomington calls for sunny skies Saturday, with a daytime high near 54°F and north-northeast winds of 7 to 9 mph, gusting as high as 18 mph. Those gusts are worth monitoring on deep throws, but overall these look like manageable conditions for the Ohio State vs Indiana passing props I am backing.