Week 10 NFL Picks Against the Spread – Early Lines to Target
- In the Week 10 NFL picks against the spread, the Detroit Lions and Jacksonville Jaguars are showing NFL-best 6-2 ATS records
- The Carolina Panthers (1-6-1) are the NFL’s worst ATS team this season, just behind both New England and Atlanta at 2-7
- All of the Week 10 NFL picks against the spread and early lines to target are outlined in the story below
Before getting into assessing the Week 10 NFL picks against the spread, a moment if you will to discuss the fine line between winning and losing.
They say that sports are a game of inches, and that certainly hit home with the Week 9 ATS picks of yours truly. A New Orleans Saints field goal that doinked off the left upright, and the right foot of Dallas Cowboys QB Dak Prescott barely touching the sideline out of bounds line on a two-point conversion attempt was the difference between a 3-0 week and the reality of a 1-2 finish.
But enough about me. Let’s move on to the NFL lines for the Week 10 ATS picks.
How quickly the San Francisco 49ers have gone from looking like Max Verstappen ripping around an F1 circuit to a broken-down jalopy limping along the freeway. Yet oddsmakers are sending the Niners out as the 3-point road chalk against the AFC South-leading Jacksonville Jaguars.
In Seattle, the Seahawks are coming home licking their wounds following a whipping at Baltimore. And there’s nothing like a visit from the Washington Commanders to cure what ails you.
Imagine a couple of years ago picking a team with Gardner Minshew under center to slap around Bill Belichick and the Patriots. How the mighty have fallen because that’s what we’re going to do as the Indianapolis Colts play New England across the pond in Germany.
Let’s check out all the top NFL picks and best early bets in the Week 10 ATS picks.
Week 10 NFL Picks Against the Spread
| Matchup | Spread | Pick | Units Risked |
|---|---|---|---|
| Indianapolis Colts vs New England Patriots | IND -1.5 | IND | 1 |
| San Francisco 49ers vs Jacksonville Jaguars | SF -3 | JAX | 1 |
| Washington Commanders vs Seattle Seahawks | SEA -6.5 | SEA | 1 |
Our top NFL ATS picks this week in the table above will feature plays on the Colts, Jaguars and Seahawks.
Odds as of November 8 at BetMGM Sportsbook. Get one of the best NFL betting promos to bet on all of your NFL Week 10 ATS picks here.
NFL ATS Picks 1: 49ers Mauled By Jaguars
Losers of three in a row following a 5-0 start, San Francisco looks to be a team in trouble. However, the 49ers are 5-0 ATS in the last five meetings with Jacksonville.
Back in The Bank with the best fans in the league 🔒#SFvsJAX | #DUUUVAL pic.twitter.com/PTDbWqiTun
— Jacksonville Jaguars (@Jaguars) November 7, 2023
This is a different Jaguars team, though, one with a real chance of gaining home field in the opening round of the playoffs. Jacksonville has won and covered in each of the last five games.
NFL ATS Picks: Jacksonville Jaguars +3 (-110), 1 unit
NFL ATS Picks 2: Seahawks Take Command
Seattle will be seeking to right the ship following last Sunday’s debacle at Baltimore. The Seahawks are 2-1-1 ATS at home this season and 4-1 ATS in the past five games against an NFC opponent.
The Commanders are 7-3 ATS in their last 10 road games and 11-6-3 in the last 20 as a betting underdog.
NFL ATS Picks: Seattle Seahawks -6.5 (-110), 1 unit
NFL ATS Picks 3: Colts Stampede Patriots
Whether you look at it straight up (2-7) or ATS (2-7), this is the worst New England team in decades. The Patriots are last in the AFC in both categories. There’s even speculation that coach Bill Belichick might not survive another loss if they drop to 2-8.
If you told me 3 years ago these would be the kind of questions asked to Bill Belichick I would say you’re a looney tune 🙃 and yet here we are… pic.twitter.com/7yS9aixOsR
— Just Cece 🏈 (@JustCeceSports) November 6, 2023
The Colts are 4-1 in picks against the spread in the last five games within the conference. Indianapolis has scored at least 20 points in 10 successive games. New England has scored less than 20 points in seven of the past eight games.
NFL ATS Picks: Indianapolis Colts -1.5 (-110), 1 unit
- NFL ATS records: 9-17-1
Week 10 NFL Picks Against the Spread Quick Picks
- Bears (-3.5) vs Panthers: It’s 2-7 vs 1-7 on the Week 10 TNF game. Chicago is at least 7-12-1 ATS in its last 20 games as a betting favorite
- Bengals (-6.5) vs Texans: Tough call here. Cincinnati is 7-2-1 ATS over the past 10 home games. Houston is 8-2 ATS in the last 10 as an underdog. But the Bengals are arguably the NFL’s hottest team right now
- Vikings (+2.5) vs Saints: Bad things tend to happen to New Orleans when playing Minnesota
- Packers (+3.5) vs Steelers: Green Bay coach Matt LaFleur is 15-7 ATS as an underdog
- Ravens (-6) vs Browns: Favorites are 8-2-1 ATS in the last 11 games between Baltimore and Cleveland when the line is 6+ points
- Cardinals (+1.5) vs Falcons: Arizona QB Kyler Murray is back and the Cardinals are 8-1 SU and 7-2 ATS in nine home games against Atlanta
- Titans (+1) vs Buccaneers: Tennessee coach Mike Vrabel is 27-17-1 ATS as a betting underdog
- Lions (-2.5) vs Chargers: Detroit is 6-2 ATS in the past eight games when holding a rest advantage over the opponent
- Cowboys (-16.5) vs Giants: Dallas won 40-0 over the Giants in Week 1 on the road. And that was with Daniel Jones at QB for NY. This week they get Tommy DeVito
- Raiders (+1) vs Jets: Las Vegas looked like a different team in the first week with Antonio Pierce as coach
- Bills (-7.5) vs Broncos: Buffalo is 5-0 ATS in the last five games against better Denver teams than this one
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An industry veteran, Bob literally taught the course on the history of sports at Elder College. He has worked as a Sports Columnist for Postmedia, appeared as a guest on several radio stations, was the Vice President of the Society For International Hockey Research in Ontario, and written 25 books.
