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Arizona Cardinals vs Minnesota Vikings Odds, Lines, Spread, and Picks NFL Week 8

Chris Amberley

by Chris Amberley in NFL Football

Updated Oct 29, 2022 · 5:00 AM PDT

Kyler Murray entrance
Oct 20, 2022; Glendale, Arizona, United States; Arizona Cardinals quarterback Kyler Murray (1) takes the field to play the New Orleans Saints at State Farm Stadium. Mandatory Credit: Joe Rondone-Arizona Republic Nfl Cardinals Saints Photos New Orleans Saints At Arizona Cardinals
  • Arizona is catching 3.5 points in the Cardinals vs Vikings odds on Sunday (Oct. 30) in Week 8 NFL action at U.S. Bank Stadium in Minneapolis, MN
  • Arizona is 15-3-2 against the spread as a road underdog under Kliff Kingsbury
  • The complete Cardinals vs Vikings odds are listed below, along with injury news and best bets

Who knew that getting their best offensive skill player back would be the key to unlocking the Cardinals’ (3-4, 2-1 away) offense?

DeAndre Hopkins returned to the Arizona lineup last week, and the Cards promptly scored 13 more points than they had previously recorded in any other game this season.

Now, Hopkins and Co. travel to Minnesota on Sunday for a date with the Vikings (5-1, 3-0 home). The NFC North leaders are perfect at home this season so far, and online sportsbooks believe that trend will continue in the Week 8 NFL odds.

Cardinals vs Vikings Odds

Team Spread Moneyline Total
Arizona Cardinals +3.5 (-110) +155 O 49 (-110)
Minnesota Vikings -3.5 (-110) -180 U 49 (-110)

Odds as of October 28 at DraftKings Sportsbook. Claim the DraftKings Sportsbook promo code.

Minnesota is currently a 3.5-point favorite, in a contest with a 49 point total. Sharp money is pounding Arizona as of Friday afternoon, so there’s a good chance this line moves down to a field goal. 56% of the spread wagers are backing the Cards, making up 83% of the ATS handle.

Kickoff for this Week 8 clash is set for 1 pm ET inside U.S. Bank Stadium in Minneapolis, MN. Fox will have the broadcast nationwide, with Chris Meyers on the call and Mark Schlereth providing color.

Arizona Cardinals Betting Analysis

The Cardinals offensive splits with and without Hopkins are pretty remarkable. When Hopkins is active Arizona averages 27 points per game. When he’s out, they average only 18 points.

Kyler Murray is 9-2 with Hopkins on the field, but just 3-7 when he sits. Murray completes 71% of his throws for over 270 yards per start when Hopkins suits up. When he’s absent, Murray’s completion rate dips to 64%, while his passing yards per game crater to 238.

As for the matchup against the Vikings, it sets up nicely for Arizona. Minnesota ranks 31st per DVOA against number one receivers, and dead last versus tight ends. As luck would have it, now that Marquise Brown is on IR, the Cards’ top-two pass catchers are Hopkins, and tight end Zach Ertz.

Defensively, Arizona is actually better than their DVOA ranking might suggest. Yes, they got their doors blown off by the Chiefs in Week 1, but don’t forget they were missing six starters. Since that loss, they actually grade out eighth in expected points added (EPA) against, and have held four of their last five opponents to 20 points or less.

On the injury front, there are offensive line concerns. C Rodney Hudson, guard Max Garcia and tackle D.J. Humphries are all questionable, while running back James Conner is out with a rib injury.

It’s worth noting that the Cards were missing a pair of starting o-linemen last week versus the Saints, and Murray still completed 69% of his passes for a season-high 7.0 yards per attempt.

Minnesota Vikings Betting Analysis

The Vikings enter play winners of five of six so far this season. But before we crown them, there’s a reason they’re not higher in the 2022 Super Bowl odds. They’ve beaten one team with a winning record, and that was a Miami squad that played two backups at QB. Even with those backups under center, the Fins still put up 458 yards of total offense.

Minny’s other four wins have come against teams with a combined 9-18 record. Kirk Cousins is off a to nice start with a 66.2 completion percentage and nine TD passes, but the Cardinals’ defensive scheme presents a problem.

Cousins’ passing grade drops from 83.9 to 50.4 when blitzed. No team has blitzed more frequently than the Cardinals this season, and we can expect another high rate given Cousins’ struggles against the heat.

Justin Jefferson is once again among the league’s top wideouts ranking third in receiving yards, but there’s reason to be pessimistic about his outlook as well. Arizona defends number one receivers exceptionally well, and has only allowed three TD’s to enemy wideouts all season.

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Cardinals vs Vikings Prediction

Defensively, Minnesota is all smoke and mirrors. We already mentioned their inefficiency defending pass catchers, and since Week 1 they rank 19th in EPA against overall.

The Vikings have covered just once in their last five games, while the Cardinals have been phenomenal as road underdogs. In the Kingsbury era, Arizona is 15-3-2 ATS as a road ‘dog, winning eight times outright.

They’ve won and covered both times as road underdogs this season, beating the closing line by an average of over 11 points.

Picks: Arizona Cardinals +3.5 (-110) 1 unit, Arizona Cardinals Over 22.5 Points (-115) 1 unit

2022 NFL Season Picks Record: 5-4, +0.47 units

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