Opening College Football Week 11 Odds, Spreads and Early Predictions

• Week 11 of the college football season begins in earnest Thursday night when #25 Pittsburgh hosts North Carolina
• The top matchup of the week has #11 Texas A&M visiting #12 Mississippi
• The full list of Week 11 opening lines and odds can be found below with predictions

Two SEC teams angling for at least New Year’s Six bowl bids highlight the Week 11 action in college football.

#11 Texas A&M (7-2) visits #12 Mississippi (7-2) at 7:00 pm ET Saturday at Vaught Hemingway Stadium in Oxford. The Aggies have won four games in a row, starting with an upset of then-#1 Alabama. The Rebels have won four of their last five games.

Other games involving ranked teams on Saturday have #4 Oklahoma (9-0) visiting #18 Baylor (7-2) in the Big 12, #9 Michigan (8-1) traveling to #23 Penn State (6-3) in the Big Ten, and #13 Wake Forest (8-1) hosting #21 North Carolina State (7-2) in the ACC.

Here is a look all the NCAAF Week 11 opening lines:

College Football Week 11 Opening Odds

Odds as of November 7th at DraftKings.

Texas A&M Looks to Extend Streak

Texas A&M defeated then-#12 Auburn 20-3 on Saturday at home as defensive end Michael Clemons scored the game’s only touchdown on a 24-yard fumble return in the fourth quarter.

I love how Michael Clemons subtly snuck that marshawn lynch celebration in jumping into the end zone….
Hold my ………..😂😂😂😂 pic.twitter.com/e1Qwpen1jb

— Brandon Leone (@BrandonLeone) November 7, 2021

Clemons’ scoop-and-score came after defensive tackle Jayden Peevy poked the ball away from scrambling Auburn quarterback Bo Nix. Clemons picked up the ball and sprinted to the end zone.

Zach Calzada finished 15 of 29 for 192 yards for Texas A&M (7-2, 4-2 SEC), shaking off an apparent injury to his non-throwing shoulder in the third quarter.

Matt Corral threw for 324 yards and a touchdown to lead Mississippi past Liberty 27-14 on Saturday at home. Corral completed 20 of 27 passes, including six completions of 20-plus yards.

This Matt Corral 50-yard dime into double coverage 😳

(via @OleMissFB)pic.twitter.com/2m3uBYrt8F

— Bleacher Report CFB (@BR_CFB) November 6, 2021

The Rebels raced to a 24-0 halftime lead, highlighted by a 70-yard touchdown run by Jerrion Ealy on the game’s second play.

Texas A&M is playing well. However, Corral and Ole Miss look attractive getting two points at home.

Sooners Try to Stay Perfect

Oklahoma will look to be one of four FBS teams to remain unbeaten when it visits Baylor at McLane Stadium in Waco, Texas.

The Sooners had the weekend off after beating Texas Tech 52-21 on Oct. 30 at home. Oklahoma has scored at least 35 points in five straight games.

Caleb Williams is on track to record the highest grade ever given to a first-year player (94.8)@OU_Football pic.twitter.com/4dffP1ZvDW

— PFF College (@PFF_College) November 1, 2021

Baylor was knocked off 30-28 at TCU on Saturday as Chandler Morris threw for 461 yards and two touchdowns in his first start for the Horned Frogs.

Baylor was driving and past midfield after TCU missed a field goal attempt when linebacker Shadrach Banks intercepted a pass thrown by Gerry Bohanon with 1:03 left.

PICKED OFF 😤

The @TCUFootball defense with a CLUTCH play in the final minute pic.twitter.com/071QsXO0n9

— FOX College Football (@CFBONFOX) November 6, 2021

Bohanon finished 14 of 20 for 214 yards with three touchdowns and two interceptions, and Abram Smith ran for 125 yards for Baylor, which had its three-game winning streak snapped. Tyquan Thornton had five catches for 121 yards and two TDs.

Baylor can be tough to beat in Waco. So, look for the Bears to at least keep things close – perhaps even pull the upset — and be worth a wager with the six points.

Out of Line?

One line that seems somewhat off is #22 Coastal Carolina being favored by 9.5 points at home against Georgia State on Saturday in a Sun Belt Conference game.

Coastal Carolina is 8-1 and coming off a convincing 28-3 win at Georgia Southern on Saturday. Georgia State is just 4-5.

The Chanticleers have become a brand-name to bettors among Group of Five schools. Look for that line to go up.