Upcoming Match-ups

Seahawks vs Colts Odds, Lines, Spread, and Picks NFL Week 1

Eric Rosales

by Eric Rosales in NFL Football

Updated Sep 10, 2021 · 7:00 PM PDT

Russell Wilson talking to Carson Wentz
Seattle Seahawks quarterback Russell Wilson (3) talks with Philadelphia Eagles quarterback Carson Wentz after an NFL football game Sunday, Dec. 3, 2017, in Seattle. The Seahawks won 24-10. (AP Photo/Ted S. Warren)
  • The Seattle Seahawks visit the Indianapolis Colts in Week 1 of the NFL season
  • The Colts have lost seven straight Week 1 games
  • Read below for odds, analysis and a betting prediction

The Seattle Seahawks know their best chance at success is to #LetRussCook. The Indianapolis Colts think a healthy Carson Wentz is the key to theirs.

Their first looks at these plans take place Sunday at Lucas Oil Field with a 1pm kickoff.

They may not be on the marquee for Week 1 of the NFL regular season, but these are two teams that expect to be factors in their respective conferences.

The Seahawks are coming off a 12-4 campaign and NFC West title, while the Colts went 11-5, clinching an AFC Wild Card berth.

Seahawks vs Colts Odds

Team Moneyline Spread Total
Seattle Seahawks -145 -2.5 (-115) O 49 (-110)
Indianapolis Colts +125 +2.5 (-105) U 49 (-110)

Odds as of  Sept. 10th at DraftKings.

The Seahawks are 2.5-point road favorites in this one, though the line can be found at -3, depending on where you’re looking. The game total is 49, but again, you can find an extra half-point (49.5) at some books.

A whopping 87% of the bets placed are on the Seahawks to cover, the same percentage taking Seattle on the moneyline. 83% of bets are on the over.

Wilson, Run D Key in Indy

The ‘Hawks will primarily go as Wilson goes. He was on fire to start last season, throwing for 2,541 yards and 28 TDs against just eight interceptions in leading Seattle to a 6-2 mark. He had multiple TD throws in each game and threw for over 300 yards in five contests.

While Seattle was an identical 6-2 in the second half of the year, Wilson stagnated. He threw for 1,671 and 12 majors, with zero 300-yard passing games and just three multiple TD-toss outings. Seattle was a playoff one-and-done, dominated by the Rams 30-20, with Wilson going just 11-for-27 for 174 yards with two TD tosses, while getting sacked five times.

The hope is new OC Shane Waldron will bring tempo and innovation from the Rams, where he was a passing game coordinator for offensive guru Sean McVay. Acquiring mammoth ex-Raiders guard Gabe Jackson should also help Wilson stay upright. DK Metcalf and TJ Lockett provide one of the premier patch-catching duos in the NFL.

Seattle’s defense, not exactly a descendant of the previous Legion of Boom-led units of the past, will be up against it in this one. While grading out to middle-of-the-pack (thank a brutal bottom-5 pass defense), their run defense a year ago was among the league’s best: their 3.5 yards per rush allowed was third best in the NFL.

Can they avoid getting grinded down against one of the league’s premier O-lines? The Colts ran the ball a lot, and cranked out 4.4 yards a tote in 2020.

Is Wentz The Final Piece?

The hope is head coach Frank Reich can coax brilliance out of Wentz, as the Colts traded for the no. 2 overall pick in the 2016 NFL draft in the offseason.

The Eagles unceremoniously dumped him after a year that watched his confidence wane, while losing his starting job to Jalen Hurts. But Wentz has probably not been fully healthy since Year 2, before tearing his ACL. Since then, he’s battled a back fracture, while also missing a playoff start due to concussion. The beat carried on in Indy — at least in the preseason.

With that foot injury hopefully in the rearview, he should enjoy the best roster he’s been set up with since that MVP campaign that ended with an injury in 2017. The Colts have a strong backfield, fronted by second-year battering ram Jonathan Taylor, with Nyheim Hines and Marlon Mack offering plenty of support.

The offensive line is stout, though Quenton Nelson (foot) and  Ryan Kelly (elbow) are dinged up heading into the opener. With Eric Fisher still recovering from an Achilles’ injury,  we’re about to find out how unproven Julién Davenport hold up at left tackle.

What’s the Best Bet?

Indy’s emphasis is getting off to a better start: they have lost seven straight Week 1 matchups. Last year, they dropped their opener to the Jaguars — Jacksonville’s lone win of the season.

Meanwhile, the Seahawks do well in the 1pm ET time slot, where they’ve won 11 of 12, including a 3-1 run in 2020 — but they were just 1-5 ATS as a road favorite last season.

Expect a well-played game with defense making an impact, keeping this one a lower-scoring affair, with Wilson getting it done on the road.

Pick:

  • Seahawks -2.5 (1 unit to win 0.87 units) 
  • UNDER 49 points (1 unit to win 0.91 units)
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