NFL Week 11 Odds – Opening Lines and Spreads for All Games

• Week 11 of the NFL season begins Thursday night with the Patriots visiting the Falcons
• The Buccaneers are the biggest favorites at 11 points at home against the Giants
• All the Week 11 opening lines and spreads can be found below with analysis

Week 11 of the NFL season begins Thursday night when the streaking New England Patriots visit the Atlanta Falcons.

The Patriots (6-4) have won four games in a row and are 5.5-point favorites. The Falcons (4-5) have lost two of their last three games.

Sunday Night Football will feature the Los Angeles Chargers (5-4) hosting the Pittsburgh Steelers (5-3-1). The Chargers have lost three of their last four games while the Steelers’ four-game winning streak ended Sunday when they were tied by the Detroit Lions.

The Tampa Bay Buccaneers are substantial 11-point favorites as they host the New York Giants on Monday Night Football. The Buccaneers (6-3) are double-digits favorites despite losing their last two games. The Giants (3-6) have won two of their past three games.

Here’s a look at all the NFL Week 11 betting lines:

NFL Week 11 Opening Odds

Odds as of November 14th at FanDuel.

Slumping Bucs Big Favorites

The Buccaneers are the biggest favorites of the week despite being in a mini slump and losing 29-19 at Washington on Sunday as Tom Brady threw two interceptions in the first quarter.

Read it like a 📖

📺 » FOX | #TBvsWAS pic.twitter.com/d19JtjwwrY

— Washington Commanders (@Commanders) November 14, 2021

Tampa Bay also suffered a blow when nose tackle Vita Vea was carted off with an injury on the final play of a 19-play, 80-yard drive over 10:26 that sealed the victory for Washington.

Brady threw two picks just like in the loss to New Orleans two weeks ago before the Buccaneers had their bye week and finished 23 of 34 for 220 yards and two touchdown passes. Brady’s picks came on two of his first six throwers one off the hands of rookie Jaelon Darden and another that was caught by Washington safety Bobby McCain.

The Giants had their bye this week after beating the Las Vegas Raiders 23-16 at home last Sunday.

Eagles, Cardinals Slight Favorites

The lowest line is 1.5 points for the Philadelphia Eagles over the visiting New Orleans Saints and the Arizona Cardinals on the road against the Seattle Seahawks.

The Eagles (4-6) won for the second time in three games Sunday, downing the Broncos 30-13 in Denver. Cornerback Darius Slay returned a fumble 82 yards for a touchdown and rookie DeVonta Smith caught two TD passes from Jalen Hurts.

Darius Slay took this fumble 82 yards to the crib 😤

(via @NFL)pic.twitter.com/2WhKj3PHvt

— Bleacher Report (@BleacherReport) November 14, 2021

The Saints dropped a 23-21 decision to the Tennessee Titans on the road Sunday for their second straight defeat since losing quarterback Jameis Winston to a season-ending knee injury.

Replacement QB Trevor Siemien was 19-of-34 passing for 298 yards and two touchdowns against the Titans, but it wasn’t enough.

TOUCHDOWN CALLAWAY!

15-yard strike from Siemian 🙌

📺: CBS pic.twitter.com/d4rMb5aneG

— New Orleans Saints (@Saints) November 14, 2021

New Orleans played without three injured starters in four-time Pro Bowl running back Alvin Kamara (knee), left tackle Terron Armstead (knee and shoulder) and defensive back C.J. Gardner-Johnson (foot).

Playing without injured quarterback Kyler Murray and wide receiver DeAndre Hopkins, the Cardinals (8-2) were routed 34-10 at home by the Carolina Panthers. Both of Arizona’s losses have come in their last three games.

The Seahawks (3-6) were blanked 17-0 to the Packers in Green Bay in QB Russell Wilson’s return from finger surgery. Seattle has dropped four of its last five games.

That's INT No. 2 for the defense!@_SmashAmos31 takes it away. 😤#SEAvsGB | #GoPackGo

📺 CBS pic.twitter.com/eaVoKPWncW

— Green Bay Packers (@packers) November 15, 2021

Line Movement

The Titans and Cleveland Browns are both double-digit home favorites — Tennessee by 10.5 points over the Houston Texans and Cleveland by 10 points over the Lions. However, it would not be surprising to see both lines go up during the week.

Even with the Titans (7-2) missing running back Derrick Henry and wide receiver Julio Jones to injury, look for the public to fade the hapless Texans (1-8), who are on an eight-game losing streak. Same thing applies for the banged-up Browns (5-5) against the Lions (0-8-1), who don’t figure to get much betting love despite breaking their eight-game skid with the tie in Pittsburgh.